气-液色谱法测定羊水半乳糖醇用于半乳糖血症的产前诊断

Gas-liquid chromatographic determination of galactitol in amniotic fluid for possible use in prenatal diagnosis of galactosaemia.

作者信息

Allen J T, Holton J B, Gillett M G

出版信息

Clin Chim Acta. 1981 Feb 19;110(1):59-63. doi: 10.1016/0009-8981(81)90300-4.

Abstract

A gas liquid chromatographic method for the estimation of galactitol in amniotic fluid from pregnancies at risk for galactosaemia is described. The method is based on the almost complete removal of glucose from the amniotic fluid by ion exchange, and the subsequent chromatography of galactitol as its hexaacetate.

摘要

本文描述了一种用于测定有半乳糖血症风险的妊娠羊水中半乳糖醇含量的气液色谱法。该方法基于通过离子交换几乎完全去除羊水中的葡萄糖，以及随后将半乳糖醇的六乙酸酯进行色谱分析。