Jara F M, Toledo-Pereyra L H
Eur Surg Res. 1980;12(5):363-8. doi: 10.1159/000128142.
The effect of venting on left atrial pressure and lung water accumulation was studied after prolonged aortic cross-clamping (90 min) and cardiopulmonary bypass in mongrel dogs. Two groups of animals, one with and one without venting, were studied. Left atrial pressure rose significantly (p less than 0.05) in the non-vented animals. This increase, however, did not allow for lung water accumulation or morphological evidence of pulmonary edema. These results appear to indicate that venting is only necessary if a normal left atrial pressure is sought during prolonged aortic cross-clamping. Since the increase in left atrial pressure did not have any detrimental effect on lung morphology or water accumulation, the role of venting under our experimental setting becomes more theoretical than necessary.
在杂种犬中，研究了在长时间主动脉交叉钳夹（90分钟）和体外循环后排气对左心房压力和肺水积聚的影响。研究了两组动物，一组排气，一组不排气。未排气的动物左心房压力显著升高（p<0.05）。然而，这种升高并未导致肺水积聚或肺水肿的形态学证据。这些结果似乎表明，只有在长时间主动脉交叉钳夹期间寻求正常左心房压力时才需要排气。由于左心房压力的升高对肺形态或水积聚没有任何有害影响，在我们的实验设置下排气的作用变得更多是理论上的而非必要的。
