Behera H N, Patnaik B K
Gerontology. 1981;27(1-2):32-6. doi: 10.1159/000212446.
Alloxan-decreased percentage solubility level of collagen in bone, skin and tendon following 4 and 28 days of treatment showed an almost complete recovery to normal levels in bone and skin after a 20-day recovery period. Alloxan effect if still maintained in tendon after repeated doses, suggesting tissue specificity of the recovery process.
在治疗4天和28天后,四氧嘧啶降低了骨、皮肤和肌腱中胶原蛋白的溶解度百分比水平,在20天的恢复期后,骨和皮肤中的胶原蛋白溶解度几乎完全恢复到正常水平。重复给药后,四氧嘧啶对肌腱的影响仍然存在,这表明恢复过程具有组织特异性。