ten Have H A, Eulderink F
Gerontology. 1981;27(1-2):42-50. doi: 10.1159/000212448.
In our morphological and kinesiological study, degenerative changes of the human cervical spine became more frequent and severe with advancing age. Disk splits and diarthrodial cartilage loss were the first lesions to appear. Apophyseal osteophytes arose approximately two decades after apophyseal cartilage loss, paradiscal osteophytes two decades after disk splits and irregularity of the vertebral end-plates 10-15 years after the appearance of paradiscal osteophytes. Because all these degenerative lesions are associated with loss of mobility, advancing age is correlated with decreasing mobility as well. In the absence of progression of any degenerative lesion, however, no change in mobility was found.
在我们的形态学和运动学研究中，人类颈椎的退行性变化随着年龄的增长而变得更加频繁和严重。椎间盘破裂和关节软骨丧失是最早出现的病变。关节突骨赘在关节突软骨丧失大约二十年后出现，椎间盘旁骨赘在椎间盘破裂二十年后出现，而椎体终板不规则在椎间盘旁骨赘出现10 - 15年后出现。由于所有这些退行性病变都与活动度丧失有关，因此年龄增长也与活动度降低相关。然而，在没有任何退行性病变进展的情况下，未发现活动度有变化。
