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[老年人痴呆与非痴呆行为障碍的多学科诊断。关于其病程及预后研究的初步探讨]

[Multidisciplinary diagnosis of dementia and non-dementia behavior disorders in the aged. Preliminary study for research on its course and prognosis].

作者信息

Jonker C, Hooijer C, Lindeboom J, Visser S L

出版信息

Gerontologie. 1981 Feb;12(1):2-13.

PMID:7215964
Abstract

The need to differentiate between dementia and the so-called functional psychiatric diseases of old age is of therapeutic as well as social importance. The main symptoms of dementia--lack of memory, disorientation and cognitive disturbances--are much less clearly defined than would be desirable, despite the neuropathological changes regarded as underlying senile dementia. The disease does not always have a progressive course. Confusion is also possible with other forms of dementia, while the symptoms of dementia can also be found in so-called functional psychiatric diseases. On the basis of the literature and/of our own research, it appears that a sharper definition of senile dementia is possible. Besides clinical criteria one can make use of--partly recently introduced--diagnostic techniques, specifically a structured psychiatric interview for old people, a neuropsychological testbattery, EEG, visual evoked response techniques and CT-brain scanning. The value of these diagnostic techniques for the diagnosis and the assessment of the prognosis of senile dementia can only be determined in a follow-up study. The set-up of such a follow-up study is described.

摘要

区分痴呆症与所谓的老年功能性精神疾病,无论在治疗方面还是社会层面都具有重要意义。尽管神经病理学变化被认为是老年性痴呆的潜在病因,但痴呆症的主要症状——记忆力减退、定向障碍和认知紊乱——远不如我们期望的那样明确。这种疾病并非总是呈进行性发展。与其他形式的痴呆症也可能存在混淆,而在所谓的功能性精神疾病中也能发现痴呆症的症状。根据文献以及我们自己的研究,似乎有可能对老年性痴呆进行更明确的定义。除了临床标准外,还可以利用——部分是最近引入的——诊断技术,特别是针对老年人的结构化精神科访谈、神经心理测试组合、脑电图、视觉诱发电位技术和脑部CT扫描。这些诊断技术对老年性痴呆的诊断和预后评估的价值,只能在一项随访研究中确定。本文描述了这样一项随访研究的设置。

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