Winek C L, Esposito F M
Forensic Sci Int. 1981 Jan-Feb;17(1):27-36. doi: 10.1016/0379-0738(81)90185-7.
Post-mortem ethanol levels in blood were compared to corresponding levels in rib bone marrow, vitreous humor, urine and bile. In forensic toxicology, a good correlation between blood and a tissue or body fluid is needed to estimate a blood alcohol concentration when blood is unavailable or contaminated. In this study, direct injection and headspace gas-chromatographic techniques were employed to quantitate the ethanol concentrations. Comparable findings by these two techniques showed a reproducibility of results. When the determined bone marrow ethanol levels were corrected for the lipid fraction, a consistent correlation could be established between ethanol levels in blood and bone marrow. The relationship (linearity and ratio range) between ethanol levels in blood and corrected levels in bone marrow was better than that between blood and vitreous humor, bile or urine. This study showed that blood ethanol levels can be predicted by extrapolating the corrected rib bone marrow ethanol level.
将血液中的死后乙醇水平与肋骨骨髓、玻璃体液、尿液和胆汁中的相应水平进行比较。在法医毒理学中，当血液无法获取或受到污染时，需要血液与组织或体液之间具有良好的相关性来估计血液酒精浓度。在本研究中，采用直接进样和顶空气相色谱技术对乙醇浓度进行定量。这两种技术得到的可比结果表明结果具有可重复性。当对测定的骨髓乙醇水平进行脂质分数校正后，血液和骨髓中的乙醇水平之间可以建立一致的相关性。血液中的乙醇水平与校正后的骨髓中的乙醇水平之间的关系（线性和比例范围）优于血液与玻璃体液、胆汁或尿液之间的关系。本研究表明，通过外推校正后的肋骨骨髓乙醇水平可以预测血液乙醇水平。
