Mesenchymal tumours of the uterus. VII. A clinicopathological study of 60 endometrial stromal nodules.

Endometrial stromal nodules are well-circumscribed neoplasms composed of cells identical to those in low-grade endometrial stromal sarcoma and proliferative endometrium. The clinical and pathologic features of 60 endometrial stromal nodules were studied to determine their characteristics and behaviour. A follow-up of up to 16 years revealed that none of the 60 patients developed recurrences or died of her disease, indicating that circumscribed endometrial stromal tumours are benign. A number os specific features such as irregularities in the margin, high mitotic counts, and a glandular trend did not seem to alter the benign course of this lesion.