Kansal V K, Malik A
Indian J Physiol Pharmacol. 1980 Oct-Dec;24(4):267-77.
The effect of protein deprivation and subsequent rehabilitation on the intestinal transport of L-methionine was studied in albino rats of both sexes. The rats given diet containing no protein or 3 per cent maize protein for 28 days, lost their intestinal cell population by 50 and 20 per cent respectively. The net absorption rate of L-methionine was little affected, while absorptive capacity of intestinal cells was considerably enhanced in protein-deficient rats. The increase in absorptive capacity of intestinal cells was much higher in rats given protein-free diet than in those given maize diet. The augmentation is absorptive capacity of intestinal cells of protein-deprived rats was a temporary adaptation to the conditions that prevent the formation of new cells. Rehabilitation of malnourished rat on diet containing 17 per cent casein, resulted in a rapid increase in intestinal cell population, return of the absorptive capacity of intestinal cells to normal, and augmentation in net absorption rates.
研究了蛋白质缺乏及随后的恢复对雌雄白化大鼠肠道L-蛋氨酸转运的影响。给予不含蛋白质或3%玉米蛋白饮食28天的大鼠，其肠道细胞数量分别减少了50%和20%。L-蛋氨酸的净吸收率受影响较小，而蛋白质缺乏大鼠肠道细胞的吸收能力显著增强。给予无蛋白饮食的大鼠肠道细胞吸收能力的增加比给予玉米饮食的大鼠高得多。蛋白质缺乏大鼠肠道细胞吸收能力的增强是对阻止新细胞形成条件的一种暂时适应。营养不良的大鼠在含17%酪蛋白的饮食上恢复，导致肠道细胞数量迅速增加，肠道细胞吸收能力恢复正常，净吸收率增加。
