Strobel-Stevens J D, Lacey J C
J Cell Physiol. 1981 Feb;106(2):201-7. doi: 10.1002/jcp.1041060205.
We present evidence that extends our earlier preliminary report on the stimulatory effect of saline washes on confluent cells in culture (Lacey et al., '77). That work suggested that an inhibitory substance was being removed by the washes. The present work suggests that the inhibitor is in the 10,000-30,000 MW range, is reversibly bound, is cationic and is also a protease inhibitor. It is heat stable, but is apparently degraded with time in our experimental systems.
我们提供的证据扩展了我们早期关于盐水冲洗对培养的汇合细胞的刺激作用的初步报告（Lacey等人，1977年）。该研究表明冲洗可去除一种抑制性物质。目前的研究表明，该抑制剂的分子量在10,000至30,000道尔顿之间，以可逆方式结合，呈阳离子性，并且还是一种蛋白酶抑制剂。它具有热稳定性，但在我们的实验系统中显然会随时间降解。
