Hillman N, Nadijcka M
J Embryol Exp Morphol. 1980 Oct;59:27-37.
The results from a comparative ultrastructural study of spermiogenesis in 6-, 10-, 14- and 17-month-old sterile t6/tw32, and fertile T/t6, T/tw32 and BALB/c, mice are reported. The studies show that all of the males contained the same types of defective spermatids and that defects were not limited to specific spermatid stages. Younger males had fewer abnormal spermatids than older males of the same genotype and at each age the BALB/c and t6/tw32 males appeared to contain more abnormal spermatids than the other males. No unique spermatid defect or increased frequency of a specific defect was found which can be correlated with infertility of the t6/tw32 males.
报道了对6个月、10个月、14个月和17个月大的不育t6/tw32小鼠以及可育的T/t6、T/tw32和BALB/c小鼠精子发生的比较超微结构研究结果。研究表明，所有雄性小鼠都含有相同类型的缺陷精子细胞，且缺陷并不局限于特定的精子细胞阶段。相同基因型的年轻雄性小鼠比年老雄性小鼠的异常精子细胞更少，并且在每个年龄段，BALB/c和t6/tw32雄性小鼠似乎比其他雄性小鼠含有更多的异常精子细胞。未发现可与t6/tw32雄性小鼠不育相关的独特精子细胞缺陷或特定缺陷频率增加的情况。
