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伊拉克南部阿布-哈西卜地区镰状细胞病的患病率。

The prevalence of sickle cell disease in Abu-AL-Khasib district of southern Iraq.

作者信息

Alkasab F M, Al-Alusi F A, Adnani M S, Alkafajei A M, Al-Shakerchi N H, Noori S F

出版信息

J Trop Med Hyg. 1981 Apr;84(2):77-80.

PMID:7218407
Abstract

At attempt was made to estimate the prevalence of sickle cell disease among the primary school children in Abul-al-Khasib district of southern Iraq which is known for a relatively high prevalence. Examination of 706 children in the age group of 10 to 12 years from 10 out of 20 schools randomly chosen in four villages of Abu-al-Khasib showed an overall prevalence rate of 16% as compared to 2.5% seen in a control population of 525 children belonging to five urban schools in Basrah. Sickle cell trait was evident in 13.3% of the cases. Sickledex was used for initial testing and those showing positive sickling phenomenon were confirmed by cellulose acetate haemoglobin electrophoresis. The need for introducing early screening measures as well as marriage/genetic counselling as part of the overall health and welfare services in stressed.

摘要

有人试图估算伊拉克南部阿布勒-哈西卜区小学生中镰状细胞病的患病率,该地区该病患病率相对较高。在阿布勒-哈西卜四个村庄随机挑选的20所学校中的10所,对706名10至12岁的儿童进行检查,结果显示总体患病率为16%,而巴士拉五所城市学校525名儿童组成的对照人群患病率为2.5%。镰状细胞性状在13.3%的病例中明显。使用镰状细胞筛检试验进行初步检测,醋酸纤维素血红蛋白电泳证实出现镰状现象呈阳性的病例。强调需要引入早期筛查措施以及婚姻/遗传咨询,作为整体健康和福利服务的一部分。

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