McCool R E, Catalona W J
J Urol. 1981 Apr;125(4):549-50. doi: 10.1016/s0022-5347(17)55101-0.
Recent clinical observations indicate that children who have undergone splenectomy for trauma have a significantly increased incidence (about 2 per cent) of subsequent fata sepsis, particularly with pneumococcus organisms. Some protection against fatal sepsis may be afforded by immunization with the newly developed pneumococcal vaccine in children more than 2 years old or by the use of prophylactic penicillin. However, splenectomy should be avoided whenever possible. The vast majority of iatrogenic splenic injuries that occur during renal operations in children are usually minor capsular lacerations that can be managed conservatively, using suturing techniques and drainage, and do not require splenectomy.
近期的临床观察表明，因创伤而接受脾切除术的儿童，随后发生致命性败血症的发生率显著增加（约2%），尤其是感染肺炎球菌。对于两岁以上儿童，接种新研发的肺炎球菌疫苗或使用预防性青霉素，可能对致命性败血症有一定的预防作用。然而，应尽可能避免进行脾切除术。儿童肾脏手术中发生的绝大多数医源性脾损伤通常为轻微的包膜撕裂伤，可采用缝合技术和引流进行保守处理，无需进行脾切除术。
