Valenti S, Segatto A, Fiorella G, Piranese A, Manani G
Minerva Anestesiol. 1980 Dec;46(12):1235-42.
Interference on the part of premedication with diazepam and trazodone with althesin anaesthesia was investigated and compared by means of variance analysis according to Fisher, and the X2c test according to Yates, in 150 patients aged 35-45 yr in three groups of 50 during examination of the uterine cavity. No marked difference between the effects of the two drugs were noted, with two exceptions: 1) trazodone was better able to potentiate the hypnotic action of althesin, so that less was needed for the induction of anaesthesia; 2) patients pretreated wih diazepam displayed a marked increase in postoperative somnolence, this being an expression of the drug's hypnotic effect.
在150名年龄在35至45岁的患者检查宫腔时，将其分为三组，每组50人，采用Fisher方差分析和Yates X2c检验，研究并比较了术前用药地西泮和曲唑酮对阿法沙龙麻醉的干扰作用。除两个例外情况外，未观察到两种药物的效果有明显差异：1）曲唑酮更能增强阿法沙龙的催眠作用，因此诱导麻醉所需的剂量更少；2）术前用地西泮治疗的患者术后嗜睡明显增加，这是该药物催眠作用的一种表现。
