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刺激对豚鼠腹下神经节多量子自发突触电位的影响。

Effects of stimulation on the multiquantal spontaneous synaptic potentials in guinea pig hypogastric ganglia.

作者信息

Bornstein J C

出版信息

Neurosci Lett. 1981 Feb 23;22(1):57-61. doi: 10.1016/0304-3940(81)90285-8.

DOI:10.1016/0304-3940(81)90285-8
PMID:7219892
Abstract

Loss frequency (0.5-2 Hz) stimulation of the preganglionic nerve produced calcium ion (Ca2+)-dependent increases in the frequency of spontaneous synaptic potentials recorded from guinea-pig hypogastric ganglion cells. The increased frequency was accompanied by a marked increase in the proportion of multiquantal spontaneous potentials and this was also dependent on extracellular Ca2+. The latter effect was interpreted as an increase in the degree of bursting within the spontaneous release process, supporting the hypothesis that the bursting is related to the cytoplasmic Ca2+ concentration.

摘要

对豚鼠下腹神经节细胞记录到的自发性突触电位频率进行节前神经的低频(0.5 - 2赫兹)刺激,会产生钙离子(Ca2+)依赖性增加。频率增加伴随着多量子自发性电位比例的显著增加,这同样依赖于细胞外Ca2+。后一种效应被解释为自发性释放过程中爆发程度的增加,支持了爆发与细胞质Ca2+浓度相关的假说。

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