Pharmacological profile of a new antilipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) (1) II - Antilipolytic and blood lipid lowering activity.
作者信息
Lovisolo P P, Briatico-Vangosa G, Orsini G, Ronchi R, Angelucci R
出版信息
Pharmacol Res Commun. 1981 Feb;13(2):163-74. doi: 10.1016/s0031-6989(81)80017-3.
PMID:7220575
Abstract
摘要
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Pharmacological profile of a new antilipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) (1) II - Antilipolytic and blood lipid lowering activity.
Pharmacol Res Commun. 1981 Feb;13(2):163-74. doi: 10.1016/s0031-6989(81)80017-3.
2
Pharmacological profile of a new anti-lipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) (1) I - Mechanism of action.
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Modulation of the hypolipidemic effect of fish oil by inhibition of adipose tissue lipolysis with acipimox, a nicotinic acid analog.使用烟酸类似物阿西莫司抑制脂肪组织脂解作用对鱼油降血脂作用的调节。
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Inhibition of lipolysis by nicotinic acid and by acipimox.烟酸和阿西莫司对脂肪分解的抑制作用。
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Effects of acipimox, a nicotinic acid derivative, on lipolysis in human adipose tissue and on cholesterol synthesis in human jejunal mucosa.
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Different acute and chronic effects of acipimox treatment on glucose and lipid metabolism in patients with type 2 diabetes.阿西莫司治疗对2型糖尿病患者糖脂代谢的不同急性和慢性影响。
Diabet Med. 1993 Dec;10(10):950-7. doi: 10.1111/j.1464-5491.1993.tb00011.x.
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Restoration of growth hormone (GH) response to GH-releasing hormone in elderly and obese subjects by acute pharmacological reduction of plasma free fatty acids.通过急性药理学降低血浆游离脂肪酸来恢复老年和肥胖受试者对生长激素释放激素的生长激素（GH）反应。
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Pronounced blood glucose-lowering effect of the antilipolytic drug acipimox in noninsulin-dependent diabetes mellitus patients during a 3-day intensified treatment period.在为期3天的强化治疗期内，抗脂解药物阿西莫司对非胰岛素依赖型糖尿病患者有显著的降血糖作用。
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Effect of acipimox, a lipid lowering drug, on growth hormone (GH) response to GH-releasing hormone in normal subjects.降脂药物阿西莫司对正常受试者生长激素（GH）释放激素刺激的生长激素（GH）反应的影响。
J Endocrinol Invest. 1990 Jun;13(6):539-42. doi: 10.1007/BF03348621.
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Acute metabolic and hormonal responses to the inhibition of lipolysis in non-obese patients with non-insulin-dependent (type 2) diabetes mellitus: effects of acipimox.非胰岛素依赖型（2型）糖尿病非肥胖患者脂肪分解抑制的急性代谢和激素反应：阿西莫司的作用
Clin Sci (Lond). 1992 May;82(5):565-71. doi: 10.1042/cs0820565.
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