柔红霉素对心肌收缩力及β-甲基地高辛作用的影响。
Effect of daunomycin on myocardial contractility and on the action of beta-methyldigoxin.
作者信息
Bossa R, Galatulas I, Spiti R
出版信息
Pharmacology. 1980;21(6):400-2. doi: 10.1159/000137460.
PMID:7220592
Abstract
In isolated electrically driven guinea pig left atria daunomycin at concentrations of 50-200 microgram/ml reduced the contraction. In the presence of daunomycin the positive inotropic effect of beta-methyldigoxin was reduced and, at higher concentration of daunomycin, contractility was inherited.
摘要
在离体电驱动的豚鼠左心房中，浓度为50 - 200微克/毫升的柔红霉素可降低收缩力。在柔红霉素存在的情况下，β-甲基地高辛的正性肌力作用减弱，且在柔红霉素浓度较高时，收缩性受到抑制。
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