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[骨与关节结核的医学治疗]

[Medical treatment of osteoarticular tuberculosis].

作者信息

Lejeune E, Bouvier M, Llorca G, André-Fouet E, Dubreuil C

出版信息

Rev Rhum Mal Osteoartic. 1981 Feb;48(2):171-80.

PMID:7221446
Abstract

The authors report 45 personal cases observed over the last ten years, from a series of 520 cases collected during a multi-centre enquiry of the French Society of Rheumatology and a review of the literature; they discuss the present tendencies in the treatment of bone and joint tuberculosis. Antibiotic and chemotherapy uses drugs which are more and more effective, easier and easier to manipulate, ensuring in almost all cases a lasting cure with frequent conservation of joint function, shortening the natural course of the disease, and preventing or curing its complications. The role of surgery thus becomes more restricted, the period of rest may be shortened and it may becomes less strict in many cases; on the other hand, physiotherapy is becoming more important in this treatment. As for the possibility of shortening antibiotic therapy, and although the experience obtained from lung tuberculosis is encouraging, the absence of comparably large series in bone and joint tuberculosis should make one circumspect.

摘要

作者报告了过去十年中观察到的45例个人病例,这些病例来自法国风湿病学会多中心调查收集的520例病例系列以及文献综述;他们讨论了骨与关节结核治疗的当前趋势。抗生素和化疗使用的药物越来越有效,越来越易于操作,几乎在所有情况下都能确保持久治愈,同时频繁保留关节功能,缩短疾病的自然病程,并预防或治愈其并发症。因此,手术的作用变得更加有限,休息期可能缩短,在许多情况下也可能不那么严格;另一方面,物理治疗在这种治疗中变得更加重要。至于缩短抗生素治疗疗程的可能性,尽管从肺结核获得的经验令人鼓舞,但骨与关节结核缺乏同等规模的系列病例,这应让人谨慎行事。

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