Fitzgerald R H, Wallace K M, Baker A S
South Med J. 1981 Apr;74(4):424-6. doi: 10.1097/00007611-198104000-00014.
Patients with lymphoma and leukemia are at increased risk of therapy-related sudden increase in the serum uric acid level, with resultant precipitation and obstruction in the more acidic and concentrated distal nephron. Appropriate pretreatment measures can prevent intrarenal crystal formation. The acute obstruction responds well to treatment, and aggressive measures are indicated.
淋巴瘤和白血病患者发生治疗相关血清尿酸水平突然升高的风险增加，导致在酸性更强且更浓缩的远端肾单位中发生沉淀和梗阻。适当的预处理措施可预防肾内晶体形成。急性梗阻对治疗反应良好，需要采取积极措施。
