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关于大鼠饮食治疗与汞吸收关系的更多数据。

More data on mercury absorption in relation to dietary treatment in rats.

作者信息

Kostial K, Blanusa M, Rabar I, Simonović I

出版信息

Toxicol Lett. 1981 Jan;7(3):201-5. doi: 10.1016/0378-4274(81)90068-0.

Abstract

The kinetics of mercury (Hg) absorption in relation to diet by determining whole body (WB), carcass (C) and gut (G) retention in control and milk-fed rats 6, 9, 12 and 15 days after oral administration of 203Hg have been studied. All retention values were higher in the milk-fed than in control rats during the experimental period. The higher WB retention in the milk-fed animals was primarily due to increased G retention especially at shorter time intervals. Animals on the milk diet had in the C, higher retention values, and in the G, higher retention and longer residence time. There was no evidence that Hg from the gut compartment entered into other parts of the body within the observation period. More evidence is needed about the effect of other dietary treatments on Hg metabolism.

摘要

通过测定口服203Hg后6、9、12和15天对照组和喂乳大鼠的全身(WB)、胴体(C)和肠道(G)汞保留量,研究了汞(Hg)吸收与饮食的动力学关系。在实验期间,喂乳大鼠的所有保留值均高于对照组大鼠。喂乳动物中较高的全身保留主要是由于肠道保留增加,尤其是在较短的时间间隔内。食用乳类饮食的动物在胴体中保留值较高,在肠道中保留值较高且停留时间较长。没有证据表明在观察期内肠道内的汞进入身体的其他部位。关于其他饮食处理对汞代谢的影响,还需要更多证据。

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