Groch M W, Lewis G K, Murphy P H, De Puey E G, Burdine J A
J Nucl Med. 1978 Oct;19(10):1131-7.
Regional myocardial wall motion is usually evaluated qualitatively from ECG-gated end-systolic and end-diastolic blood-pool images. Radionuclide kymography, which displays a one-dimensional scintigraphic image in time, synchronized with the electrocardiogram, provides a method to quantitate this motion. The technique is analogous to M-mode ultrasound in that one dimension is displayed as a function of time, but the activity distribution is displayed in place of acoustic interfaces. The motion of regional myocardial segments can be measured from multiple kymographic projections across the cardiac blood pool, after equilibration of a radioactive tracer. Radionuclide kymography is potentially better quantitatively than gated blood-pool imaging and is not hindered by viewing windows as are single- and multiple-transducer ultrasonography. Regional wall motion determined from radionuclide kymography correlated well with that determined from contrast left ventriculography in a series of patients. Since the kymographic sweep is initiated by the R wave of the ECG and proceeds continuously throughout the cardiac cycle, the temporal sequence of regional myocardial contraction can be directly assessed and related to corresponding portions of the ECG.
局部心肌壁运动通常通过心电图门控的收缩末期和舒张末期血池图像进行定性评估。放射性核素记波摄影术可在与心电图同步的时间内显示一维闪烁图像，为定量评估这种运动提供了一种方法。该技术类似于M型超声，即一维图像显示为时间的函数，但显示的是放射性分布而非声学界面。在放射性示踪剂达到平衡后，可从横跨心脏血池的多个记波摄影投影测量局部心肌节段的运动。放射性核素记波摄影术在定量方面可能比门控血池成像更好，并且不像单换能器和多换能器超声检查那样受观察窗的限制。在一系列患者中，通过放射性核素记波摄影术确定的局部壁运动与通过对比左心室造影确定的结果相关性良好。由于记波扫描由心电图的R波启动，并在整个心动周期中持续进行，因此可以直接评估局部心肌收缩的时间顺序，并将其与心电图的相应部分相关联。
