兔主动脉同种异体移植内皮的扫描电子显微镜研究：硫唑嘌呤、泼尼松龙和异丙嗪对早期细胞侵袭的影响
Scanning electron-microscope studies of the endothelium of aortic allografts in the rabbit: effect of azathioprine, prednisolone and promethazine on early cellular invasion.
作者信息
Reidy M A, Bowyer D E
出版信息
J Pathol. 1978 Jan;124(1):1-5. doi: 10.1002/path.1711240102.
PMID:722367
Abstract
Aortic allografts in rabbits were observed by scanning electron microscopy 24 hr after transplantation. The extent of the leucocytic invasion could be precisely and reproducibly measured. Azathioprine and prednisolone, whether alone or in combination, given on three occasions--10 hr before, immediately after and again 10 hr after surgery, significantly inhibited the cellular invasion. Promethazine produced a slight, but not statistically significant, effect.
摘要
在移植后24小时，通过扫描电子显微镜观察兔的主动脉同种异体移植物。可以精确且可重复地测量白细胞浸润的程度。硫唑嘌呤和泼尼松龙，无论单独使用还是联合使用，在手术前10小时、手术后立即以及手术后10小时再次给药三次，均能显著抑制细胞浸润。异丙嗪产生了轻微但无统计学意义的效果。
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