Civatte J, Belaich S, Bonvalet D, Vallet C, Broissin M
Ann Med Interne (Paris). 1980;131(7):427-30.
A total of 678 cases of soft chancre were treated in one hospital between 1973 and 1979. The majority of the patients were males (97 p. cent), and most of them came originally from Maghreb or Black Africa. Contamination was from prostitution (61 p. cent) or chance acquaintances (29 p. cent). The genital ulceration was often clinically atypical, frequently syphiloid; pain was present in only 59 p. cent of cases, and adenopathy, noted in 63 p. cent of patients, had the appearance of an inflammatory bubo in only 23 p. cent. The present high frequency of soft chancres, and their misleading clinical characteristics, makes it sometimes difficult to establish the clinical differential diagnosis from syphilitic chancre, but confirmation of the latter is supplied by direct examination and culture to search for Ducreys bacillus, this being indispensable for establishing the correct diagnosis. Treatment with sulfamethoxazole trimethopin or streptomycin prevents complications and cures the affection in one or two weeks.
1973年至1979年间，一家医院共治疗了678例软下疳患者。大多数患者为男性（97%），他们大多来自马格里布或黑非洲。感染途径为嫖娼（61%）或偶然结识（29%）。生殖器溃疡在临床上常不典型，多呈梅毒样；仅59%的病例有疼痛，63%的患者有淋巴结病，其中仅23%表现为炎性腹股沟淋巴结炎。目前软下疳发病率较高，且临床特征易误导，有时难以与梅毒硬下疳进行临床鉴别诊断，但通过直接检查和培养寻找杜克雷氏杆菌可确诊梅毒硬下疳，这对正确诊断必不可少。用磺胺甲恶唑甲氧苄啶或链霉素治疗可预防并发症，并在一两周内治愈该病。
