Margolis S, Martin L
Ann Ophthalmol. 1980 Dec;12(12):1378-81.
We have described a unilateral anophthalmia in an infant with normal chromosome studies born to parents who took LSD before and during pregnancy. In view of the lack of any other fetal abnormalities in this child, known to be associated with LSD, we report this case to suggest that anophthalmia may be a new drug-related defect. A complete drug history of the parents should be taken in cases of congenital abnormalities to accumulates further data, which will point conclusively to the etiology of anophthalmia and possibly other congenital defects.
我们描述了一名染色体检查正常的婴儿单侧无眼症病例，其父母在孕期前后服用过麦角酸二乙酰胺（LSD）。鉴于该患儿不存在已知与LSD相关的其他胎儿异常情况，我们报告此病例以提示无眼症可能是一种新的药物相关缺陷。对于先天性异常病例，应获取父母完整的用药史以积累更多数据，这将最终明确无眼症以及可能其他先天性缺陷的病因。
