Pace M, Sportiello V
Arch Sci Med (Torino). 1980 Apr-Jun;137(2):289-91.
After a little introduction about the elements that normally caused an elevation of the LAP-serum (leucine-aminopeptidase), the authors point out the elevation of this enzyme in subjects with neoplastic diseases especially in the female genitalia. The authors will have studied in this work the LAP comportment in subjects with bronchial neoplasm; the authors found in 12 cases of bronchial malignant neoplasm controlled by histological-test (biopsy during bronchoscopy a constant elevation of serum LAP that they relate for causes not certain, to the neoplasm presence. Was not elevation in the metastases pulmonary neoplasm. the authors conclude pointing out the LAP a very important element in precocious diagnosis of neoplastic diseases also the bronchial level, when this elevation in the serum not find explanation in a pathological hepatic disease.
在对通常导致血清亮氨酸氨基肽酶（LAP）升高的因素做了简要介绍后，作者指出该酶在患有肿瘤疾病的患者中会升高，尤其是在女性生殖器肿瘤患者中。作者在这项研究中研究了支气管肿瘤患者的LAP表现；作者在12例经组织学检查（支气管镜检查时活检）确诊的支气管恶性肿瘤病例中发现，血清LAP持续升高，他们将其归因于肿瘤的存在，但原因尚不明确。肺转移瘤患者中未出现LAP升高。作者总结指出，当血清中LAP升高无法用病理性肝病解释时，LAP在肿瘤疾病的早期诊断中是一个非常重要的指标，在支气管肿瘤方面也是如此。
