Parameswaran M, Arinze I J
Biochim Biophys Acta. 1981 Jan 21;672(2):219-23. doi: 10.1016/0304-4165(81)90396-2.
Liver mitochondria isolated from fetal and newborn guinea pigs synthesized phosphoenolpyruvate at 4-6 nmol/min per mg protein with 2 mM malate, succinate, and alpha-ketoglutarate as substrates. These rates were 90-110% of that by adult liver mitochondria and were not substantially altered in the second half of gestation or within 24 h after birth. Both palmitoyl- and octanoylcarnitine were inhibitory to phosphoenolpyruvate synthesis in adult and fetal preparations, but free octanoate was inhibitory only in adult liver mitochondria.
从胎儿和新生豚鼠分离出的肝脏线粒体，以2 mM苹果酸、琥珀酸和α-酮戊二酸作为底物时，每毫克蛋白质合成磷酸烯醇丙酮酸的速率为4 - 6 nmol/分钟。这些速率是成年肝脏线粒体的90 - 110%，在妊娠后半期或出生后24小时内没有显著变化。棕榈酰肉碱和辛酰肉碱对成年和胎儿制剂中的磷酸烯醇丙酮酸合成均有抑制作用，但游离辛酸仅对成年肝脏线粒体有抑制作用。
