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[乙醇和苹果白兰地对Wistar大鼠上消化道和食管无影响。法国西部食管癌病因学因素评估研究项目的一部分(作者译)]

[Absence of effect of ethanol and apple brandy on the upper digestive tract and esophagus of the Wistar rat. Part of a research project to assess etiological factors of cancer of the esophagus in the west of France (author's transl)].

作者信息

Mandard A M, Marnay J, Hélie H, Tuyns A J, Le Talaer J Y

出版信息

Bull Cancer. 1981;68(1):49-58.

PMID:7225607
Abstract

Epidemiological studies have shown the role of alcohol in esophageal cancer in the West of France. Experiments were undertaken on Wistar rats to study the effect of locally consumed alcoholic beverages on the esophagus. Neither histological modifications, precancerous lesions nor cancer were observed in the animals. There was no significant excess of benign or malignant tumours in treated animals when compared with controls.

摘要

流行病学研究表明了酒精在法国西部食管癌发病中的作用。对Wistar大鼠进行了实验,以研究当地消费的酒精饮料对食管的影响。在这些动物中未观察到组织学改变、癌前病变或癌症。与对照组相比,接受处理的动物中良性或恶性肿瘤均无显著过量。

相似文献

1
[Absence of effect of ethanol and apple brandy on the upper digestive tract and esophagus of the Wistar rat. Part of a research project to assess etiological factors of cancer of the esophagus in the west of France (author's transl)].[乙醇和苹果白兰地对Wistar大鼠上消化道和食管无影响。法国西部食管癌病因学因素评估研究项目的一部分(作者译)]
Bull Cancer. 1981;68(1):49-58.
2
[Research on the etiological factors of oesophageal cancer in the West of France (author's transl)].法国西部食管癌病因学因素的研究(作者译)
Bull Cancer. 1980;67(1):15-28.
3
Effect of an apple brandy from Normandy and of ethanol on epithelial cell proliferation in the esophagus of rats.
Digestion. 1987;37(3):184-92. doi: 10.1159/000199498.
4
Detection of mutagens in various alcoholic beverages, particularly in apple brandy, a product of western France.
Dev Toxicol Environ Sci. 1980;8:287-90.
5
[Nutrition, alcohol and oesophageal cancer (author's transl)].
Bull Cancer. 1978;65(1):58-64.
6
[Cancer of the esophagus induced in the Wistar rat by ethyl-N-butyl-nitrosamine].
Bull Cancer. 1984;71(5):419-24.
7
[Ethanol and carcinogenesis].
Leber Magen Darm. 1982 Jun;12(3):95-107.
8
[Effect of alcohol on the digestive tract].
Rev Hosp Clin Fac Med Sao Paulo. 1982 Feb;37(1):30-42.
9
The existence of an NAD-dependent pathway for retinoic acid formation from vitamin A (retinol) in rat esophagus and its inhibition by ethanol and histamine 2 (H2) receptor antagonists.大鼠食管中存在一条由维生素A(视黄醇)生成视黄酸的NAD依赖性途径及其受乙醇和组胺2(H2)受体拮抗剂抑制的情况。
Med Sci Monit. 2003 Dec;9(12):BR403-6.
10
[The digestive tract and alcohol].
Internist (Berl). 1978 Feb;19(2):116-22.

引用本文的文献

1
Balloon cytology in screening of asymptomatic alcoholics for esophageal cancer, Part I.
Dig Dis Sci. 1985 Sep;30(9):845-51. doi: 10.1007/BF01309515.