Timins B I, Gutman J A, Haft J I
Chest. 1981 Apr;79(4):477-9. doi: 10.1378/chest.79.4.477.
A 57-year-old woman with right bundle branch block +LPH and ventricular premature contractions developed complete heart block (CHB) following administration of disopyramide phosphate (Norpace). The ECG at the onset of CHB suggested block to have occurred in the trifascicular conduction system. On rechallenging the patient with the drug following the implantation of a permanent pacemaker, intermittent complete heart block developed. This case suggests that disopyramide should be used with caution in patients with bifascicular block patterns on ECG.
一名57岁女性，患有右束支传导阻滞+左后分支阻滞及室性早搏，在服用磷酸丙吡胺（诺佩斯）后发生了完全性心脏传导阻滞（CHB）。CHB发作时的心电图提示阻滞发生在三分支传导系统。在植入永久性起搏器后再次给该患者使用该药时，出现了间歇性完全性心脏传导阻滞。该病例提示，对于心电图有双分支阻滞图形的患者，使用丙吡胺时应谨慎。
