金黄色葡萄球菌剥脱毒素在小鼠葡萄球菌感染中的作用。
Role of Staphylococcus aureus exfoliatin toxin in staphylococcal infections in mice.
作者信息
Shibl A M
出版信息
Chemotherapy. 1981;27(3):224-7. doi: 10.1159/000237982.
PMID:7226975
Abstract
Clindamycin at a concentration of 0.18 microgram/ml reduced growth of Staphylococcus aureus in vitro by 40% but inhibited exfoliatin toxin production by 90%. Mice infected with S. aureus and subsequently treated with clindamycin did not exfoliate but still died.
摘要
浓度为0.18微克/毫升的克林霉素在体外使金黄色葡萄球菌的生长减少了40%，但使剥脱毒素的产生受到了90%的抑制。感染了金黄色葡萄球菌并随后接受克林霉素治疗的小鼠没有出现皮肤脱落，但仍然死亡。
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