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Use of adenine nucleotide derivatives to assess the potential of exo-active-site-directed reagents as species- or isozyme-specific enzyme inactivators. 2. Isozyme-specific inactivation of a mammalian enzyme and its significance in the possible design of fetal isozyme targeted antineoplastic agents.

作者信息

Hampton A, Kappler F, Maeda M, Patel A D

出版信息

J Med Chem. 1978 Nov;21(11):1137-40. doi: 10.1021/jm00209a009.

DOI:10.1021/jm00209a009
PMID:722719
Abstract
摘要

相似文献

1
Use of adenine nucleotide derivatives to assess the potential of exo-active-site-directed reagents as species- or isozyme-specific enzyme inactivators. 2. Isozyme-specific inactivation of a mammalian enzyme and its significance in the possible design of fetal isozyme targeted antineoplastic agents.使用腺嘌呤核苷酸衍生物评估外活性位点导向试剂作为物种或同工酶特异性酶失活剂的潜力。2. 一种哺乳动物酶的同工酶特异性失活及其在可能设计的靶向胎儿同工酶的抗肿瘤药物中的意义。
J Med Chem. 1978 Nov;21(11):1137-40. doi: 10.1021/jm00209a009.
2
Use of adenine nucleotide derivatives to assess the potential of exo-active-site-directed reagents as species- or isozyme-specific enzyme inactivators. 5. Interactions of adenosine 5'-triphosphate derivatives with rat pyruvate kinases, Escherichia coli thymidine kinase, and yeast and rat hexokinases.使用腺嘌呤核苷酸衍生物评估外活性位点导向试剂作为物种或同工酶特异性酶失活剂的潜力。5. 5'-三磷酸腺苷衍生物与大鼠丙酮酸激酶、大肠杆菌胸苷激酶以及酵母和大鼠己糖激酶的相互作用。
J Med Chem. 1982 Apr;25(4):386-92. doi: 10.1021/jm00346a011.
3
Use of adenine nucleotide derivatives to assess the potential of exo-active-site-directed reagents as species- or isozyme-specific enzyme inactivators. 3. Synthesis of adenosine 5'-triphosphate derivatives with N6- or 8-substituents bearing iodoacetyl groups.
J Med Chem. 1982 Apr;25(4):373-81. doi: 10.1021/jm00346a009.
4
[Properties of pyruvate kinase isozyme from rat ascites hepatoma 13 cells].
Josai Shika Daigaku Kiyo. 1984;13(1):1-17.
5
Use of adenine nucleotide derivatives to assess the potential of exo-active-site-directed reagents as species- or isozyme-specific enzyme inactivators. 4. Interactions of adenosine 5'-triphosphate derivatives with adenylate kinases from Escherichia coli and rat tissues.使用腺嘌呤核苷酸衍生物评估外活性位点导向试剂作为物种或同工酶特异性酶失活剂的潜力。4. 腺苷5'-三磷酸衍生物与大肠杆菌和大鼠组织中的腺苷酸激酶的相互作用。
J Med Chem. 1982 Apr;25(4):382-6. doi: 10.1021/jm00346a010.
6
Extraction of a factor from Ehrlich ascites tumor cells that increases the activity of the fetal isozyme of pyruvate kinase in mouse liver.从艾氏腹水瘤细胞中提取一种能提高小鼠肝脏丙酮酸激酶胎儿同工酶活性的因子。
Cancer Res. 1975 Jan;35(1):180-8.
7
Interrelationships and functions of the pyruvate kinase isozymes and their variant forms: a review.
Cancer Res. 1977 Feb;37(2):341-53.
8
[Pyruvate kinase of rat hepatoma, placenta and fetal liver].[大鼠肝癌、胎盘及胎儿肝脏中的丙酮酸激酶]
C R Acad Hebd Seances Acad Sci D. 1971 Feb 22;272(8):1169-72.
9
Effects of amino acids on the kinetic properties of three noninterconvertible rat pyruvate kinases.
Arch Biochem Biophys. 1974 Aug;163(2):570-80. doi: 10.1016/0003-9861(74)90516-5.
10
Pyruvate kinase isozymes in various tissues of rat, and increase of spleen-type pyruvate kinase in liver by injecting chromatins from spleen and tumor.
J Biochem. 1976 Jan;79(1):203-15. doi: 10.1093/oxfordjournals.jbchem.a131048.