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Cell assembly patterns of embryonic mouse cerebellar cells on carbohydrate-derivatized polylysine culture substrata.胚胎小鼠小脑细胞在碳水化合物衍生化聚赖氨酸培养基质上的细胞组装模式。
J Cell Biol. 1981 Apr;89(1):54-61. doi: 10.1083/jcb.89.1.54.
2
Enhanced neuronal expression in reaggregating cells of mouse cerebellum cultured in the presence of poly-L-lysine.
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Poly(N-(4-aminobutyl)-acrylamide) as mimetic polylysine for improving survival and differentiation of cerebellar granule neurons.聚[N-(4-氨基丁基)丙烯酰胺]作为模拟聚赖氨酸提高小脑颗粒神经元的存活和分化。
J Biomed Mater Res B Appl Biomater. 2018 Apr;106(3):1194-1201. doi: 10.1002/jbm.b.33932. Epub 2017 May 31.
4
Poly (L-lysine) and poly (D-lysine) conjugates of methotrexate: different inhibitory effect on drug resistant cells.甲氨蝶呤的聚（L-赖氨酸）和聚（D-赖氨酸）缀合物：对耐药细胞的不同抑制作用。
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[Studies on the cytotoxicity of poly-L-arginine, poly-L-lysine and DEAE-dextran in L-cells and mouse embryonic fibroblasts].
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Effect of basic polycations and proteins on purified insulin receptor. Insulin-independent activation of the receptor tyrosine-specific protein kinase by poly(L-lysine).碱性聚阳离子和蛋白质对纯化胰岛素受体的作用。聚（L-赖氨酸）对受体酪氨酸特异性蛋白激酶的非胰岛素依赖性激活。
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Tuning the properties of elastin mimetic hybrid copolymers via a modular polymerization method.通过模块化聚合方法对弹性蛋白模拟杂化共聚物的性能进行调谐。
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Two forms of cerebellar glial cells interact differently with neurons in vitro.两种形式的小脑神经胶质细胞在体外与神经元的相互作用不同。
J Cell Biol. 1984 Jan;98(1):193-204. doi: 10.1083/jcb.98.1.193.
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Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.弱碱和离子载体可迅速且可逆地提高培养的小鼠成纤维细胞内吞小泡的pH值。
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Regional differences in the distribution of endogenous receptors for carbohydrate constituents of cellular glycoconjugates, especially lectins, in cortex, hippocampus, basal ganglia and thalamus of adult human brain.
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本文引用的文献

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The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins.表面碳水化合物在肝脏对循环糖蛋白的识别和转运中的作用。
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胚胎小鼠小脑细胞在碳水化合物衍生化聚赖氨酸培养基质上的细胞组装模式。

Cell assembly patterns of embryonic mouse cerebellar cells on carbohydrate-derivatized polylysine culture substrata.

作者信息

Hatten M E

出版信息

J Cell Biol. 1981 Apr;89(1):54-61. doi: 10.1083/jcb.89.1.54.

DOI:10.1083/jcb.89.1.54
PMID:7228900
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2111769/
Abstract

Four carbohydrate derivatives of poly-D-lysine have been synthesized and assayed as substrates for the tissue culture of embryonic mouse cerebellar cells. On poly-beta-(D-glucopyranosyl)-poly-D-lysine and on poly-beta-(N-acetyl-D-glucosaminyl)-poly-D-lysine, dissociated cerebellar cells formed a monolayer. On poly-beta-(D-galactopyranosyl)-poly-D-lysine, cellular aggregates were formed and cables of processes were extended between the aggregates. On poly-beta-(L-fucosyl)-poly-D-lysine, cerebellar cells failed to attach and died within 24 h. On poly-(N-acetyl)-poly-D-lysine, cell attachment was identical to that on poly-D-lysine. At low concentrations of underivatized poly-D-lysine (0.5-2.0 microgram/ml) dissociated embryonic cerebellar cells formed cellular aggregates, whereas at higher concentrations of poly-D-lysine monolayering was extensive.

摘要

已合成了四种聚-D-赖氨酸的碳水化合物衍生物，并将其作为胚胎小鼠小脑细胞组织培养的底物进行了测定。在聚-β-(D-吡喃葡萄糖基)-聚-D-赖氨酸和聚-β-(N-乙酰-D-葡糖胺基)-聚-D-赖氨酸上，解离的小脑细胞形成了单层。在聚-β-(D-吡喃半乳糖基)-聚-D-赖氨酸上，形成了细胞聚集体，并且在聚集体之间延伸出突起束。在聚-β-(L-岩藻糖基)-聚-D-赖氨酸上，小脑细胞未能附着并在24小时内死亡。在聚-(N-乙酰)-聚-D-赖氨酸上，细胞附着情况与在聚-D-赖氨酸上相同。在低浓度的未衍生化聚-D-赖氨酸（0.5 - 2.0微克/毫升）下，解离的胚胎小脑细胞形成细胞聚集体，而在较高浓度的聚-D-赖氨酸下，单层形成广泛。