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肠道放射性损伤的外科治疗。在7301例接受放射治疗的患者中出现了171处放射性损伤,其中53例患者接受了手术治疗(作者译)

[Surgical treatment of intestinal radio-lesions. 53 patients operated, out of 171 radio-lesions among 7301 irradiated (author's transl)].

作者信息

Verhaeghe M, Laurent J C, Dupont A, Madelain M, Rohart J

出版信息

J Chir (Paris). 1981 Apr;118(4):221-9.

PMID:7228928
Abstract

Results of a complete and homogenous series by the Medical Team of the Centre Anti-Cancéreux.--2,45% of abdomino-pelvic irradiations among 6516 cases,--but only 0.78 are serious and need surgery (i.e. 1/3 of the radio-lesions). The study concerned 65 cases;--during the same period, medical treatment alone controlled 51 cases of rectitis and 51 stenoses. The interval after irradiation is variable: 33 times, it was shorter than 1 year, in 32 cases, it was longer, up to 13 years. The plan for therapy is to continue the medical treatment as well as possible and to operate only in case of absolute need, but before obstruction;--to prefer immediate resection to internal derivation. The 27 resections resulted in 18 recoveries and 9 cases of peritonitis. In spite of the serious nature of the initial irradiated lesion, followed by this complicated radio-lesion, we observed: 28% of 5-year survivals, and over 10 years in 9 cases.

摘要

癌症防治中心医疗团队的完整且同质系列研究结果。——在6516例病例中,腹盆腔照射占2.45%,——但只有0.78%的情况严重,需要手术(即放射性损伤的三分之一)。该研究涉及65例病例;——在同一时期,单纯药物治疗控制了51例直肠炎和51例狭窄。照射后的间隔时间各不相同:33次短于1年,32次较长,最长达13年。治疗方案是尽可能继续药物治疗,仅在绝对必要且在梗阻前进行手术;——优先选择立即切除而非内转流术。27例切除术中有18例康复,9例发生腹膜炎。尽管最初的照射损伤严重,随后又出现这种复杂的放射性损伤,但我们观察到:5年生存率为28%,9例存活超过10年。

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