高效液相色谱法同时测定维拉帕米及其七种代谢物 - Suppr

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Simultaneous determination of verapamil and its seven metabolites by high-performance liquid chromatography.

作者信息

Kuwada M, Tateyama T, Tsutsumi J

出版信息

J Chromatogr. 1981 Mar 13;222(3):507-11. doi: 10.1016/s0378-4347(00)84156-0.

DOI:10.1016/s0378-4347(00)84156-0

PMID:7228962

Abstract

摘要

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Simultaneous determination of verapamil and its seven metabolites by high-performance liquid chromatography.高效液相色谱法同时测定维拉帕米及其七种代谢物

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Determination of the enantiomers of verapamil and norverapamil in serum using coupled achiral-chiral high-performance liquid chromatography.采用非手性-手性联用高效液相色谱法测定血清中维拉帕米和去甲维拉帕米的对映体

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引用本文的文献

Inter- and intra-subject variation in the first-pass elimination of highly cleared drugs during chronic dosing. Studies with deuterated verapamil.慢性给药期间高清除率药物首过消除的个体间和个体内差异。氘代维拉帕米的研究。

Eur J Clin Pharmacol. 1984;26(1):47-53. doi: 10.1007/BF00546708.

Antiarrhythmic actions of verapamil against ischaemic arrhythmias in the rat.维拉帕米对大鼠缺血性心律失常的抗心律失常作用。

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Calcium antagonists. Pharmacokinetic properties.钙拮抗剂。药代动力学特性。

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An investigation of the cause of accumulation of verapamil during regular dosing in patients.对患者常规给药期间维拉帕米蓄积原因的调查。

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Clinical pharmacokinetics of verapamil, nifedipine and diltiazem.维拉帕米、硝苯地平和地尔硫䓬的临床药代动力学。

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Column-switching high-performance liquid chromatography for on-line simultaneous determination and resolution of enantiomers of verapamil and its metabolites.柱切换高效液相色谱法用于在线同时测定维拉帕米及其代谢物对映体并进行拆分。

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