Sordillo E M, Sordillo P P, Hajdu S I, Good R A
J Dermatol Surg Oncol. 1981 Mar;7(3):235-9. doi: 10.1111/j.1524-4725.1981.tb00632.x.
A case of lymphangiosarcoma of a lower extremity is described in a patient with chronic lymphedema of that leg from a filarial infection in childhood. Histologically, the neoplasm resembled lymphangiosarcomas that arise in arms that become lymphedematous after mastectomies, but was different in that it also contained areas of calcification consistent with prior filarial infection. Calcifications were also present in muscle uninvolved by the lymphangiosarcoma of this case. The prolonged survival of this patient is unlike that of most patients with lymphangiosarcoma, which is generally shorter. Although lymphedema after filariasis is common, this is the first case of a lymphangiosarcoma arising in chronic lymphedema of filarial origin.
本文描述了一例下肢淋巴管肉瘤病例，患者童年时因丝虫感染导致该腿部慢性淋巴水肿。组织学上，该肿瘤类似于乳房切除术后上肢发生淋巴水肿时出现的淋巴管肉瘤，但不同之处在于它还含有与既往丝虫感染相符的钙化区域。在该病例未受淋巴管肉瘤累及的肌肉中也存在钙化。该患者的长期存活情况与大多数淋巴管肉瘤患者不同，后者的存活时间通常较短。虽然丝虫病后的淋巴水肿很常见，但这是第一例起源于丝虫性慢性淋巴水肿的淋巴管肉瘤病例。
