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蛋清蛋白微胶囊和微球的制备。

Preparation of egg albumin microcapsules and microspheres.

作者信息

Ishizaka T, Endo K, Koishi M

出版信息

J Pharm Sci. 1981 Apr;70(4):358-63. doi: 10.1002/jps.2600700404.

Abstract

Protein microspheres and microcapsules containing fine hydrophilic particles (spherical silica gel beads, iron hydrous oxidemodified nylon 12, or phenacetin) were prepared by using water-soluble egg albumin, which is heat-coagulable at 50-80 degrees. The size and size distribution of the microspheres and microcapsules formed and the microencapsulation percentage of fine particles were determined, and the factors affecting them were studied. Favorable conditions are suggested to obtain phenacetin-containing microcapsules in high yield.

摘要

使用水溶性蛋清蛋白制备了含有精细亲水性颗粒(球形硅胶珠、水合氧化铁改性尼龙12或非那西丁)的蛋白质微球和微胶囊,该蛋清蛋白在50-80摄氏度时可热凝固。测定了形成的微球和微胶囊的尺寸及尺寸分布以及细颗粒的微囊化率,并研究了影响它们的因素。提出了有利于高产率获得含非那西丁微胶囊的条件。

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