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Cholesterol crystals in osteoarthritic joint effusions.

作者信息

Fam A G, Pritzker K P, Cheng P T, Little A H

出版信息

J Rheumatol. 1981 Mar-Apr;8(2):273-80.

PMID:7230158
Abstract

Cholesterol crystals were demonstrated in synovial fluids from 4 patients with knee osteoarthritis and recurrent synovial effusions. Large crystals (10-80 micros) were readily identifiable by their characteristic plate-like morphology. Some fluids also contained numerous smaller (1-5 microns) irregular, rod and needle shaped crystals. Identification of these crystals as cholesterol was established by x-ray diffraction analysis (2 fluids) and by ultrastructural studies (1 fluid). This study documents the occurrence of cholesterol crystals in osteoarthritic effusions, but their precise pathogenetic significance remains unclear.

摘要

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