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法洛四联症修复术中保守性漏斗部切除术24小时后右心室残余压力的下降。

The drop of residual right ventricular pressure 24 hours after conservative infundibulectomy in repair of tetralogy of Fallot.

作者信息

Goor D A, Smolinksy A, Mohr R, Caspi J, Shem-Tov A

出版信息

J Thorac Cardiovasc Surg. 1981 Jun;81(6):897-905.

PMID:7230857
Abstract

Because of late complications such as right ventricular (RV) dysfunction and sudden death after tetralogy repair, a modification in the technique of total repair of tetralogy of Fallot is sought. In this study a shorter than usual conal incision and limited division of only the parietal muscle bands were utilized in 17 patients. The mean RV pressure at the end of the operation was 84 mm Hg; 24 hours later it had dropped to 55 mm Hg. The mean RV/LV pressure ratio at the end of the operation was 0.85, and 24 hours later it was 0.48. Pressure measurements were also taken at the end of the operation, at four predetermined points along the RV outflow tract. It was found that 40% of the average residual obstruction was located at the level of the infundibular ostium, 50% at the level of the conus, and 10% at the pulmonary valve. It is concluded that a 40% drop in the RV/LV pressure ratio can be anticipated to occur in less than 24 hours in cases in which (1) the contractility of the infundibular ostium and conus is preserved by conservative infundibulectomy and (2) there is a residual obstruction at a muscular level. This is on condition that the passage between the crista and the anterior conal wall is of adequate size.

摘要

由于法洛四联症修复术后存在右心室功能障碍和猝死等晚期并发症,因此寻求对法洛四联症全修复技术进行改良。在本研究中,17例患者采用了比通常更短的圆锥切口,仅有限地分离了壁肌束。手术结束时右心室平均压力为84毫米汞柱;24小时后降至55毫米汞柱。手术结束时右心室/左心室平均压力比为0.85,24小时后为0.48。还在手术结束时沿右心室流出道的四个预定点进行了压力测量。结果发现,平均残余梗阻的40%位于漏斗部开口水平,50%位于圆锥部水平,10%位于肺动脉瓣水平。得出的结论是,对于以下情况的病例,预计在不到24小时内右心室/左心室压力比会下降40%:(1)通过保守的漏斗部切除术保留漏斗部开口和圆锥部的收缩力;(2)在肌肉层面存在残余梗阻。前提是嵴与前圆锥壁之间的通道大小足够。

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