Orlovskiĭ V F
Kardiologiia. 1978 Nov;18(11):124-8.
The excretion of water, electrolytes and osmotically active substances and the blood plasma natriuretic activity were studied following isotonic dilation of the extracellular space in experiments on rabbits with ischemic cerebral hypertension. Rabbits with hypertension were marked by the phenomenon of exaggerated natriuresis and increased excretion of water and osmotically active substances after volumetric stimulation, which was due to a greater inhibition of processes of tubular reabsorption than in intact animals. The increase in the content of the natriuretic factor in the blood plasma of rabbits with ischemic cerebral hypertension after an increase in the volume of extracellular fluid could not be identified as one of the possible causes of inhibition of sodium reabsorption.
在患有缺血性脑高血压的家兔实验中,研究了细胞外液等渗扩张后水、电解质和渗透活性物质的排泄以及血浆利钠活性。高血压家兔的特点是在容量刺激后出现利钠作用过度和水及渗透活性物质排泄增加的现象,这是由于肾小管重吸收过程受到的抑制比正常动物更大。细胞外液量增加后,缺血性脑高血压家兔血浆中利钠因子含量的增加不能被确定为抑制钠重吸收的可能原因之一。