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系统性念珠菌病中的皮肤损害(作者译)

[Skin lesions in systemic candidiasis (author's transl)].

作者信息

de Prost Y, Rondeau P, Vernant J P, Touraine R

出版信息

Nouv Presse Med. 1981 May 16;10(22):1813-5.

PMID:7232170
Abstract

Skin lesions in systemic candidiasis are erythematous maculopapules and maculonodules which appear at the onset of the septicaemic phase. Their presence, especially when associated with diffuse myalgia, suggest the diagnosis which must be confirmed by haemocultures, histological examination of the skin with PAS stain and culture of skin fragments in Sabouraud's medium. Systemic candidiasis with skin lesions seems to be mainly due to Candida tropicalis and to occur with great frequency in patients with underlying blood disease. Of the three cases reported here, one concerned a 24-year-old man with premyelocytic acute leukaemia, the second a 45-year-old woman with drug-induced agranulocytosis and the third one a man aged 25 admitted to hospital for peritonitis secondary to Crohn's disease.

摘要

系统性念珠菌病的皮肤损害为红斑性斑丘疹和斑结节,出现在败血症期开始时。它们的出现,尤其是与弥漫性肌痛相关时,提示诊断,必须通过血培养、用PAS染色进行皮肤组织学检查以及在沙氏培养基中培养皮肤碎片来确诊。伴有皮肤损害的系统性念珠菌病似乎主要由热带念珠菌引起,并且在患有潜在血液疾病的患者中频繁发生。这里报告的三例中,一例是一名24岁的早幼粒细胞急性白血病男性,第二例是一名45岁药物性粒细胞缺乏症女性,第三例是一名25岁因克罗恩病继发腹膜炎入院的男性。

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