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记忆障碍、眼睑条件反射、惊吓与定向反应(作者译)

[Memory disturbances, eyelid conditioning, startle and orienting reactions (author's transl)].

作者信息

Serdaru M, Lhermitte F

出版信息

Rev Neurol (Paris). 1981;137(1):39-47.

PMID:7232965
Abstract

Patients with memory disturbances were submitted to eyelid classical conditioning procedure in which a sound was reinforced at a 50 p. 100 rate by an air puff. They were compared to normal subjects and to patients with unilateral forebrain lesions. Six patients with mesodiencephalic lesions (mamillary bodies, fornix, cingulum) didn't have any conditioning while 2 patients with bilateral temporal lesions had normal conditioning. Startle and orienting reactions were very weak too in patients with mesodiencephalic lesions and normal in patients with bilateral temporal lesions. The startle and orienting reaction impairment can be related to attention disturbances leading to the lack of conditioning.

摘要

患有记忆障碍的患者接受了眼睑经典条件反射程序,其中声音以50%的概率通过吹气得到强化。将他们与正常受试者以及单侧前脑损伤的患者进行比较。6例中脑间脑病变(乳头体、穹窿、扣带)患者没有任何条件反射,而2例双侧颞叶病变患者有正常的条件反射。中脑间脑病变患者的惊吓和定向反应也非常微弱,而双侧颞叶病变患者的惊吓和定向反应正常。惊吓和定向反应受损可能与注意力障碍有关,导致条件反射缺失。

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