Stäubli M, Studer H
Schweiz Med Wochenschr. 1981 Mar 28;111(13):460-5.
The efficacy of amiodarone in the treatment of cardiac arrhythmias is discussed in the light of published results and our own experience. Oral and intravenous administration are compared with respect to electrophysiologic changes in the heart. The possibility that these changes are mediated by amiodarone-induced inhibition of metabolic pathways in cardiac tissue which depends on thyroid hormone is discussed. Among the undesirable effects, chief consideration is given to thyroid function disturbances.
