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犬延髓锥体慢性损伤后皮质刺激的运动效应

Motor effects of cortical stimulation after chronic lesion of medullary pyramid in the dog.

作者信息

Górska T, Woolsey C N, Wetzel A

出版信息

Acta Neurobiol Exp (Wars). 1980;40(5):861-79.

PMID:7234516
Abstract

In dogs with unilateral pyramidal lesions the motor cortex on both hemispheres was stimulated under Nembutal anesthesia to study the effects of pyramidotomy upon cortically induced movements. Pyramidal lesions resulted in an almost complete abolition of foretoes flexions and marked reduction of wrist ventriflexions. Other movements were not noticeably affected, except for their increased thresholds. The increase in the thresholds of movements elicited from the affected hemispheres diminished as a function of the length of postoperative survival period, so that 6 mo after pyramidotomy the thresholds on the operated side approximated the values obtained on the normal hemispheres.

摘要

在患有单侧锥体束病变的狗中,在戊巴比妥麻醉下刺激双侧半球的运动皮层,以研究锥体束切断术对皮层诱发运动的影响。锥体束病变导致前趾弯曲几乎完全消失,腕关节掌屈明显减少。其他运动除阈值增加外,未受到明显影响。从受影响半球诱发的运动阈值增加随着术后存活时间的延长而减小,因此在锥体束切断术后6个月,手术侧的阈值接近正常半球所获得的值。

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