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[慢性创伤后骨髓炎中分离出的微生物群落对化疗制剂的敏感性]

[Sensitivity to chemotherapeutic preparations of microflora isolated in chronic posttraumatic osteomyelitis].

作者信息

Grinmaer T V, Chernomordik A B, Panchenko M K, Ozerianskaia N M, Bulycheva N P

出版信息

Antibiotiki. 1981 Apr;26(4):280-4.

PMID:7235667
Abstract

Chronic post-traumatic osteomyelitis was mainly caused (59.3 per cent) by various gramnegative bacteria. Staphylococcus, Proteus and P. aeruginosa was most frequent. Bacteria were most frequently isolated from associations of 2-5 species and not from monocultures. However, when the patient microflora was studied in dynamics, the whole associations could not be detected in every of the cases. Sensitivity of the causative agents to 23 antibacterial drugs was tested and it was found that the majority of the organisms were sensitive to gentamicin, rifampicin, biseptol, hydroxyquinolines (5-NOK, enteroseptol), furazolidon (except P. aeruginosa). P. aeruginosa was in addition sensitive to polymyxin. Proteus and other enterobacteria were sensitive to nevigramon, staphylococci and other grampositive bacteria were sensitive to oxacillin, lincomycin, novobiocin and fusidin.

摘要

慢性创伤后骨髓炎主要由各种革兰氏阴性菌引起(59.3%)。葡萄球菌、变形杆菌和铜绿假单胞菌最为常见。细菌最常从2 - 5种菌的组合中分离出来,而非单一培养物。然而,当对患者的微生物群进行动态研究时,并非在每个病例中都能检测到整个组合。对病原菌对23种抗菌药物的敏感性进行了测试,发现大多数微生物对庆大霉素、利福平、必思添、羟基喹啉(5 - NOK、肠乐美)、呋喃唑酮敏感(铜绿假单胞菌除外)。此外,铜绿假单胞菌对多粘菌素敏感。变形杆菌和其他肠杆菌对萘啶酸敏感,葡萄球菌和其他革兰氏阳性菌对苯唑西林、林可霉素、新生霉素和夫西地酸敏感。

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Antibiotiki. 1981 Apr;26(4):280-4.
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