镰状细胞血症中的骨坏死（作者译）
[Osteonecrosis in drepanocytemia (author's transl)].
作者信息
Delahaye R P, Doury P, Pattin S, Metges P J, Marchesseau J P
出版信息
Med Trop (Mars). 1978 Mar-Apr;38(2):223-8.
PMID:723569
Abstract
Aseptic osteonecrosis is due to local hypoxemia related to the sickling process. Its frequency in the U.S.A. is 8,5 p. 100 for heterozygotic patients and 0,2 p. 100 for homozygotic ones. It is rare in AS status but frequent in the double heterozygotism SC. Alcoholism, hyperlipidemia, hyperuricemia, cortisonic treatments and pregnancy are facilitating factors. For vascular causes the femoral epiphysises are most often affected. Radiological features are described.
摘要
无菌性骨坏死是由于与镰状化过程相关的局部低氧血症所致。在美国，杂合子患者的发病率为每100人中有8.5例，纯合子患者为每100人中有0.2例。在镰状细胞贫血（AS）状态下罕见，但在双重杂合子状态（SC）中常见。酗酒、高脂血症、高尿酸血症、皮质激素治疗和妊娠是促成因素。就血管性病因而言，股骨骨骺最常受累。文中描述了其放射学特征。
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