Cimino T, Spezia C, Marietti G
Arch Sci Med (Torino). 1980 Jul-Sep;137(3):471-5.
In view of the current interest in changes in serum bile acids during diseases of the liver, an assessment was made of their prognostic significance, following their determination with standard hospital laboratory equipment. Increases over normal values were found to be related to the degree of liver cell damage, i.e. maximal in acute forms, and decidedly lower in aggressive chronic and persistent hepatitis and silent cirrhosis. The results are regarded as an encouragement to experiment new, quicker methods of determination.
鉴于目前人们对肝脏疾病期间血清胆汁酸变化的关注,我们使用标准医院实验室设备测定血清胆汁酸后,对其预后意义进行了评估。发现高于正常值的情况与肝细胞损伤程度有关,即在急性形式中最高,而在侵袭性慢性和持续性肝炎以及隐匿性肝硬化中则明显较低。这些结果被视为鼓励尝试新的、更快的测定方法。