Ageev A K
Arkh Patol. 1981;43(4):10-8.
Morphological examinations of the hemopoietic system in 43 patients died of different forms of leukemias revealed irregular involvement into the leukemic processes of its different parts. Differences in the spread of leukemic lesions in the spleen, lymph nodes, tonsils and other lymphoid formations in lympho- and myeloleukemias were demonstrated. They are discussed from the point of view of the concept on metastatic involvement of different parts of the hemopoietic system in leukemias and on the importance in the development of these lesions of the cellular microenvironment. Also, the importance of atrophic changes of the thymus and other lymphoid structures as manifestations of immunological insufficiency which is one of the most significant conditions for the development of leukemia is discussed.
对43例死于不同类型白血病患者的造血系统进行形态学检查，发现其不同部位受白血病进程累及的情况不规则。已证实淋巴细胞白血病和髓细胞白血病在脾脏、淋巴结、扁桃体及其他淋巴组织中白血病病变扩散存在差异。从白血病中造血系统不同部位转移累及的概念以及细胞微环境在这些病变发生中的重要性角度对这些差异进行了讨论。此外，还讨论了胸腺及其他淋巴结构萎缩性改变作为免疫功能不全表现的重要性，免疫功能不全是白血病发生的最重要条件之一。
