Pomeranz G A, Bunt A H, Kalina R E
Arch Ophthalmol. 1981 May;99(5):857-63. doi: 10.1001/archopht.1981.03930010857014.
A 29-year-old white women had ocular melanocytosis with scleral pigmentation and a diffuse choroidal nevus. The eye was enucleated because of two choroidal tumors. Light and electron microscopy showed two separate choroidal melanomas with differential cytologic characteristics. The extreme rarity of multicentric choroidal melanomas support the belief that ocular melanocytosis predisposes to malignancy.
一名29岁的白人女性患有眼黑变病,伴有巩膜色素沉着和弥漫性脉络膜痣。因两个脉络膜肿瘤而摘除了眼球。光镜和电镜检查显示有两个具有不同细胞学特征的独立脉络膜黑色素瘤。多中心脉络膜黑色素瘤极为罕见,这支持了眼黑变病易引发恶性肿瘤的观点。