Williams C S, Siddique I H, Sapp W J
Br J Exp Pathol. 1981 Apr;62(2):165-71.
An electron microscopic study on the histopathological changes in the kidneys of pregnant hamsters resulting from infection with Leptospira canicola was undertaken. The experiment revealed damage to the glomeruli as well as the tubules. The severity of these lesions increased with the progress of the disease and examination of kidney sections showed leptospires in the tissue. It is suggested that the stress of pregnancy has some influence on the severity of the lesions seen in this disease.
对感染犬钩端螺旋体的怀孕仓鼠肾脏组织病理学变化进行了电子显微镜研究。实验发现肾小球和肾小管均有损伤。这些病变的严重程度随着疾病的进展而增加,肾脏切片检查显示组织中有钩端螺旋体。研究表明,怀孕的应激状态对该疾病中所见病变的严重程度有一定影响。