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癌症早期检测原则

Principles of early detection of cancer.

作者信息

Miller D G

出版信息

Cancer. 1981 Mar 1;47(5 Suppl):1142-5. doi: 10.1002/1097-0142(19810301)47:5+<1142::aid-cncr2820471313>3.0.co;2-6.

DOI:10.1002/1097-0142(19810301)47:5+<1142::aid-cncr2820471313>3.0.co;2-6
PMID:7237370
Abstract

Screening for the early detection of cancer offers the potential of increasing the number of patients whose cancer is diagnosed in a localized, curable stage. The operation of an efficient and effective early detection program requires that a number of conditions be fulfilled, some of which are difficult to attain. First, the target population for screening should be defined demographically and epidemiologically so that the screening program is designed to be responsive to the needs of that group, e.g., age, ethnic composition, special occupational or environmental circumstances. Furthermore, an appropriate means of communicating with the reference population must be established so that the group can be educated regarding cancer prevention and detection and motivated to use early detection programs. Screening for early detection should be carried out on two levels: primary screening for the identification of risk factors, and prescriptive screening for additional procedures ordered according to the patterns of risk factors, and prescriptive screening for additional procedures ordered according to the patterns of risk factors identified. The screening encounter should be an opportunity for health education regarding primary prevention, as well as early detection of cancer. Screening without follow-up for diagnosis and treatment is likely to be counterproductive; the patient must be provided with a means of entering the health care system when this is indicated by the screening examination. Follow-up of suspicious findings must also be carried out for end-result evaluation. Primary screening can be carried out successfully by allied health personnel under most circumstances. A program employing these principles is now being utilized by a number of independent clinics in a voluntary collaborative program called "CANSCREEN." Examples of the operational modes of this program will be presented.

摘要

癌症早期检测筛查有可能增加在癌症处于局部可治愈阶段时被诊断出的患者数量。要开展一个高效且有效的早期检测项目,需要满足一些条件,其中有些条件很难实现。首先,应从人口统计学和流行病学角度定义筛查的目标人群,以便设计出能满足该群体需求的筛查项目,例如年龄、种族构成、特殊职业或环境情况等。此外,必须建立与目标人群沟通的合适方式,以便向该群体进行癌症预防和检测方面的教育,并促使他们使用早期检测项目。早期检测筛查应在两个层面上进行:一级筛查用于识别风险因素,以及根据识别出的风险因素模式安排额外检查的规范性筛查。筛查过程应是开展一级预防以及癌症早期检测健康教育的契机。只进行筛查而不跟进诊断和治疗很可能会适得其反;当筛查检查表明有必要时,必须为患者提供进入医疗保健系统的途径。还必须对可疑结果进行跟进以评估最终结果。在大多数情况下,专职医疗人员可以成功进行一级筛查。现在,一些独立诊所正在一个名为“癌症筛查”的自愿合作项目中采用遵循这些原则的项目。将介绍该项目的运作模式示例。

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