Abu-Hakima R, Faye I
Cell Tissue Res. 1981;217(2):311-20. doi: 10.1007/BF00233583.
Three types of hemocytes are found in the Cecropia pupa, plasmatocytes, granular cells, and spherule cells. The granular cells are the major phagocytic blood cells, taking up the bacterium Enterobacter cloacae when this is injected into the pupae. Disintegrating blood cells are observed near the pericardial tissue. No other changes in ultrastructure are noted in hemocytes and pericardial cells which could be correlated with the immune response in these pupae. The fat body cells from pupae injected with bacteria contain abundant RER and Golgi bodies, whereas those from wounded (saline injected) and untreated controls do not. The fat body is the only tissue that responds to bacterial injection by increased incorporation of 3H-uridine into RNA. These findings support the idea that the fat body is the main site of synthesis of the immune proteins.
在天蚕蛹中发现了三种血细胞，即浆血细胞、颗粒细胞和小球细胞。颗粒细胞是主要的吞噬血细胞，当将阴沟肠杆菌注入蛹中时，它们会摄取这种细菌。在心包组织附近观察到血细胞解体。在血细胞和心包细胞中未发现其他与这些蛹的免疫反应相关的超微结构变化。注射细菌的蛹的脂肪体细胞含有丰富的粗面内质网和高尔基体，而受伤（注射生理盐水）和未处理的对照蛹的脂肪体细胞则没有。脂肪体是唯一通过增加3H-尿苷掺入RNA来响应细菌注射的组织。这些发现支持了脂肪体是免疫蛋白合成主要部位的观点。
