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因滥用非那西丁导致的溶血性贫血和硫化血红蛋白血症:一例具有多脏器不良反应的病例

Hemolytic anemia and sulfhemoglobinemia due to phenacetin abuse: a case with multivisceral adverse effects.

作者信息

Basset P, Bergerat J P, Lang J M, Oberling F, Gillet B

出版信息

Clin Toxicol. 1981 Apr;18(4):493-9. doi: 10.3109/15563658108990274.

DOI:10.3109/15563658108990274
PMID:7237975
Abstract

The authors report a case of recurrent sulfhemoglobinemia resulting from a chronic abuse of phenacetin. Cyanosis was accompanied by hemolytic anemia and numerous features of tissue aging. While phenacetin was found to be the oxidizing drug, no source of sulfur was identified. The origin of sulfhemoglobinemia in man is discussed and the possible role of intraerythrocytic glutathione is emphasized.

摘要

作者报告了一例因长期滥用非那西丁导致的复发性硫血红蛋白血症病例。发绀伴有溶血性贫血和许多组织老化特征。虽然发现非那西丁是氧化药物,但未确定硫的来源。文中讨论了人类硫血红蛋白血症的起源,并强调了红细胞内谷胱甘肽的可能作用。

相似文献

1
Hemolytic anemia and sulfhemoglobinemia due to phenacetin abuse: a case with multivisceral adverse effects.因滥用非那西丁导致的溶血性贫血和硫化血红蛋白血症:一例具有多脏器不良反应的病例
Clin Toxicol. 1981 Apr;18(4):493-9. doi: 10.3109/15563658108990274.
2
Phenacetin-induced sulfhemoglobinemia: report of a case and review of the literature.非那西丁诱发的硫化血红蛋白血症:一例报告及文献复习
Johns Hopkins Med J. 1976 Oct;139(4):175-7.
3
Phenacetin-induced hemolytic anemia.非那西丁所致溶血性贫血。
Can Med Assoc J. 1972 Apr 8;106(7):770-5.
4
[Phenacetin-induced hemolytic anemia misdiagnosed as unstable hemoglobinopathy].
Rinsho Ketsueki. 1992 Aug;33(8):1036-40.
5
[Hemolytic anemia caused by excessive use of analgesics].
Wiad Lek. 1992 Jan;45(1-2):52-4.
6
[A case of hemolytic anemia due to phenacetin abuse].
Rinsho Ketsueki. 1984 May;25(5):692-8.
7
Latent oxidative damage to erythrocytes and Heinz body formation in vitro: a study of an acetophenetidin abuser.
Nihon Ketsueki Gakkai Zasshi. 1982 Feb;45(1):44-9.
8
Drug induced sulphaemoglobinaemia and heinz body anaemia in pregnancy with involvement of the foetus.
Scott Med J. 1967 Sep;12(9):320-2. doi: 10.1177/003693306701200906.
9
Mechanisms of drug-induced hemolytic anemia.药物性溶血性贫血的机制。
Adv Intern Med. 1972;18:59-76.
10
[Phenacetin-induced immune hemolytic anemia of the so-called innocent bystander reaction type].
Schweiz Med Wochenschr. 1970 Sep 26;100(39):1650-2.

引用本文的文献

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Adverse effects of drugs on the blood.
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